Clinical Trials

RECRUITING
Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation
This is an open-label prospective, single institution, Phase II study of pembrolizumab in combination with radiation therapy and CSF-1R inhibition in ...
Conditions:
TNBC - Triple-Negative Breast Cancer Breast Cancer
Locations:
📍 Los Angeles, California, United States
RECRUITING
Intratreatment FDG-PET During Radiation Therapy for Gynecologic and Gastrointestinal Cancers
This study expands on protocol (NCT01908504"PET adaptive RT") designed to evaluate the utility of adaptive PET-CT planning for radiation therapy (RT)....
Conditions:
Cancer of the Cervix Vulvar Cancer Esophageal Cancer Anal Canal Cancer
Locations:
📍 Durham, North Carolina, United States
RECRUITING
Pilot Trial of Adaptive Radiotherapy Boost for HNSCC
The purpose of the study is to determine if it is feasible to use magnetic resonance imaging (MRI) to adjust a portion of radiation therapy for patien...
Conditions:
Squamous Cell Carcinoma Head and Neck Cancer
Locations:
📍 Tampa, Florida, United States
RECRUITING
Evaluation of Proton Therapy in Pediatric Cancer Patients
This is a Phase IV clinical trial observing and evaluating the safety of proton therapy in children. Protocol therapy is not being done as part of thi...
Conditions:
Tumor
Locations:
📍 Memphis, Tennessee, United States
NOT_YET_RECRUITING
M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis
The purpose of this research study is to test the ability of a mobile device application (MyCap) to collect patient information about their radiation ...
Conditions:
Radiation Dermatitis
Locations:
📍 Winston-Salem, North Carolina, United States
RECRUITING
EMST and Swallowing in Long-Term Survivors of HNCA
This study is a randomized trial examining the impact of expiratory muscle strength training (EMST) on oral intake, swallowing function, and swallow-r...
Conditions:
Head and Neck Neoplasms Deglutition Disorders
Locations:
📍 Milwaukee, Wisconsin, United States
📍 Milwaukee, Wisconsin, United States
RECRUITING
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33
The purpose of this research study is to determine if application of near infrared energy to the forehead can change blood flow in the brains of peopl...
Conditions:
Major Depressive Disorder
Locations:
📍 Boston, Massachusetts, United States
📍 New York, New York, United States
📍 Orangeburg, New York, United States
RECRUITING
Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer
This phase II trial studies the effect of calorie reduction while undergoing stereotactic ablative radiation therapy in treating patients with breast ...
Conditions:
Anatomic Stage 0 Breast Cancer AJCC v8 Anatomic Stage 1 Breast Cancer AJCC v8 Anatomic Stage 2 Breast Cancer AJCC v8 Anatomic Stage 3 Breast Cancer AJCC v8
3 more conditions available...
Locations:
📍 Philadelphia, Pennsylvania, United States
RECRUITING
Stereotactic Body Radiation and Tumor Treating Fields for Locally Advanced Pancreas Cancer
The purpose of this clinical trial is to determine whether using chemotherapy followed by stereotactic ablative body radiation therapy (SABR) and tumo...
Conditions:
Pancreas Cancer Locally Advanced Locally Advanced Pancreatic Adenocarcinoma
Locations:
📍 Miami, Florida, United States
RECRUITING
SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma
This phase II trial with a safety run-in component will evaluate whether the addition of pembrolizumab to Stereotactic Body Radiation Therapy (SBRT) r...
Conditions:
Head and Neck Squamous Cell Carcinoma (HNSCC)
Locations:
📍 Tucson, Arizona, United States
📍 Tampa, Florida, United States
📍 Weston, Florida, United States
📍 Louisville, Kentucky, United States
17 more locations available...
RECRUITING
Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer
This early-phase trial tests the safety and side effects of a tolinapant given together with radiation therapy in treating patients with head and neck...
Conditions:
Head and Neck Carcinoma of Unknown Primary Locally Advanced Head and Neck Squamous Cell Carcinoma Locally Advanced Hypopharyngeal Squamous Cell Carcinoma Locally Advanced Laryngeal Squamous Cell Carcinoma
2 more conditions available...
Locations:
📍 Atlanta, Georgia, United States
RECRUITING
MW151 and Whole-brain Radiotherapy in Patients With Intracranial Metastases
HYPOTHESIS: MW151 intervention during whole-brain radiotherapy for intracranial metastases is safe and will mitigate neurocognitive decline. RATIONAL...
Conditions:
Cognitive Dysfunction, Cognitive Disorder
Locations:
📍 Winfield, Illinois, United States
RECRUITING
MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas
This trial uses magnetic resonance elastography (MRE) to estimate tissue stiffness (hardness or softness of the tissue) in tissue that is affected by ...
Conditions:
Glioma
Locations:
📍 Houston, Texas, United States
RECRUITING
A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia
This study will assess the efficacy and safety of bilateral intra-parotid administration of AAV2-hAQP1 in adults with Grade 2 or Grade 3 radiation-ind...
Conditions:
Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
Locations:
📍 Gilbert, Arizona, United States
📍 Miami, Florida, United States
📍 Iowa City, Iowa, United States
📍 Baltimore, Maryland, United States
7 more locations available...
NOT_YET_RECRUITING
Study Examining the Safety and Toxicity of Stereotactic Body Radiotherapy (SBRT) Followed by PCX12 Immunotherapy Delivered by Intratumoral Injection for the Treatment of Patients With Locally Advanced Pancreatic Adenocarcinoma (LAPC)
The purpose of this study is to determine whether a new treatment combining radiation therapy with PCX12 is safe and tolerable.
Conditions:
Pancreatic Adenocarcinoma
Locations:
📍 Rochester, New York, United States

Total Trials: 61 - 75 of 1076